Sodium Azide → HCID 90411866, compound

Participants

Reaction Conditions

Reaction Steps

A solution of (4-(3-bromopropoxy)phenyl)(4-Iodophenyl)methanone (50.0 g, 112 mmol), and sodium azide (10.2 g, 157 mmol) was dissolved in DMF (300 ml). The reaction was heated to 45° C. and left to stir overnight. Upon completion, the reaction mixture was filtered to remove sodium salt and concentrated under reduced pressure. The crude was then further extracted with chloroform, the organic layer was washed with brine, and dried over anhydrous sodium sulfate to afford 40.3 g (88.0% yield) of (4-(3-azidopropoxy)phenyl)(4-iodophenyl)methanone as grey solid.

Provenance & Evidence