Trifluoroacetic acid methylene chloride → HCID 90411411, compound

Participants

Reaction Steps

tert-butyl-(2-(2-(2-(2-((4-(4-(3-azidopropoxy)benzoyl)phenyl)-amino)ethoxy)ethoxy)ethoxy)ethyl)-carbamate (1.75 g, 2.91 mmol) was dissolved in a solution of DCM:TFA (2:1, 12 ml) and left to stir for ca. 1 h. Upon completion, reaction was then concentrated under reduced pressure, co-evaporated with toluene, and left on oil pump for 5 hs to yield 1.52 g (97.0% yield) of (2-(2-(2-(2-((4-(4-(3-azidopropoxy)benzoyl)phenyl)-amino)ethoxy)ethoxy)ethoxy)ethyl)carboxylic acid as colorless oil.

Provenance & Evidence