HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenylethanol → HCID 72948341, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenylethanol | HCID 6054 | — |
| Reactant | Tricyclo(3.3.1.1'3,7)dec-1-ylmethanol | HCID 64556 | — |
| Reactant | 5-chloro-2,4-difluoro-N-(methylsulfonyl)benzamide | HCID 58042417 | — |
| Reactant | 5-chloro-N-(N,N-dimethylsulfamoyl)-2,4-difluorobenzamide | HCID 86702836 | — |
| Product | HCID 72948341 | HCID 72948341 | — |
Reaction Steps
Following the procedure as described in Example 8 and making variations as required to replace 5-chloro-2,4-difluoro-N-(methylsulfonyl)benzamide with 5-chloro-N—(N,N-dimethylsulfamoyl)-2,4-difluorobenzamide and adamantan-1-ylmethanol with 2-phenylethanol, the title compound was obtained as a colorless solid (0.06 g, 15%): 1H NMR (300 MHz, DMSO-d6) δ 11.76 (s, 1H), 7.72 (d, J=7.5 Hz, 1H), 7.37-7.21 (m, 6H), 4.36 (t, J=6.8 Hz, 2H), 3.09 (t, J=6.8 Hz, 2H), 2.87 (s, 6H); MS (ES−) m/z 399.1, 401.1 (M−1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08933236B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-f894158e85044bbeac45ab2bccec1823 |
| Source note | uspto-grants-2015_01 |