5-Bromo-1-(2,6-dichlorophenyl)-3,4-dihydro-7-methoxy-2(1H)-quinolinone → 5-(2-Chloro-5-fluorophenyl)-1-(2,6-dichlorophenyl)-3,4-dihydro-7-methoxy-2(1H)-quinolinone
Reaction equation
[Br:1][c:2]1[c:3]2[c:8]([cH:9][c:10]([O:12][CH3:13])[cH:11]1)[N:7]([c:14]1[c:15]([Cl:21])[cH:16][cH:17][cH:18][c:19]1[Cl:20])[C:6](=[O:22])[CH2:5][CH2:4]2.[Cl:23][c:24]1[c:25]([B:31]([OH:32])[OH:33])[cH:26][c:27]([F:30])[cH:28][cH:29]1.[Cl:34][c:35]1[cH:36][cH:37][cH:38][c:39]([Cl:40])[c:41]1[N:42]1[c:43]2[c:44]([c:45](-[c:46]3[cH:47][cH:48][c:49]([F:50])[cH:51][c:52]3[F:53])[cH:54][c:55]([O:56][CH3:57])[cH:58]2)[CH2:59][CH2:60][C:61]1=[O:62]>>[c:2]1(-[c:25]2[c:24]([Cl:23])[cH:29][cH:28][c:27]([F:30])[cH:26]2)[c:3]2[c:8]([cH:9][c:10]([O:12][CH3:13])[cH:11]1)[N:7]([c:14]1[c:15]([Cl:21])[cH:16][cH:17][cH:18][c:19]1[Cl:20])[C:6](=[O:22])[CH2:5][CH2:4]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-949d0d7192204d408ae8b64c5525d2fa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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