Methanol → HCID 86700080, compound

Participants

Reaction Conditions

Reaction Steps

Thionyl chloride (0.8 ml) was added to a suspension of 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid (400 mg) in methanol (9 ml) at 0° C. The reaction mixture was stirred at 70° C. overnight. The reaction mixture was returned to room temperature and concentrated under reduced pressure. The resulting residue was washed with saturated aqueous sodium bicarbonate and water, and then further washed with diethyl ether to give 304 mg of the title compound as a solid.

Provenance & Evidence