m-Chloroperbenzoic acid → HCID 178504590, compound

Participants

Reaction Steps

3-(6-(Methylthio)pyrimidin-4-yl)-1,3a-dihydropyrazolo[1,5-a]pyrimidin-2-amine (22′, 7.2 g, 27.9 mmol) was suspended/dissolved in 70 mL of DMF and stirred at 0° C. while mCPBA (8.0 g, 34.8 mmol) in 20 mL of DMF was added drop wise over 30 minutes. After addition, the reaction was stirred for an additional hour at ambient temperature. The ppt was isolated via suction filtration, and washed with acetonitrile, and finally ethyl ether and air dried. Isolated 5.1 g of solid (66.7% yield)

Provenance & Evidence