Benzene → Phenyl propenyl ketone

HRID 1428444Notes

Reaction equation

HRID 1428444 reaction equation
[CH:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:7](Cl)(=[O:11])/[CH:8]=[CH:9]/[CH3:10].[Cl-].[Al+3].[Cl-].[Cl-]>ClCCl>[C:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:11])/[CH:8]=[CH:9]/[CH3:10]

Participants

5

Reactant 3

HCID 241BenzeneHCID 643131trans-Crotonyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 231934Phenyl propenyl ketone

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Benzene (1 mL), crotonoyl chloride (236 mg), and aluminium chloride (280 mg) were reacted in dichloromethane (1.5 mL) at from −30° C. to room temperature for 16 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (66 mg).

Workup

  1. additionThe resultant was treated in the same manner

Sources & evidence

ORD record
ord-a2c583fdae14416b98895aa44421cec9
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

Loading…