2-Methoxynaphthalene → HCID 70926842, compound

HRID 1428448Notes

Reaction equation

HRID 1428448 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1.[C:13](Cl)(=[O:17])/[CH:14]=[CH:15]/[CH3:16].[Cl-].[Al+3].[Cl-].[Cl-]>ClCCl>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:13](=[O:17])/[CH:14]=[CH:15]/[CH3:16])[CH:9]=2)[CH:4]=1

Participants

5

Reactant 3

HCID 71192-MethoxynaphthaleneHCID 643131trans-Crotonyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 70926842HCID 70926842, compoundYield 69%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-methoxynaphthalene (158 mg), crotonoyl chloride (124 mg), and aluminium chloride (150 mg) were reacted in dichloromethane (1.5 mL) at from 0° C. to room temperature for 4 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (156 mg).

Workup

  1. additionThe resultant was treated in the same manner

Sources & evidence

ORD record
ord-0590f7b89d0a4a8d86a68d6af6b27efd
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

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