M-Xylene → HCID 46913387, compound

HRID 1428453Notes

Reaction equation

HRID 1428453 reaction equation
[C:1]1([CH3:8])[CH:6]=[CH:5][CH:4]=[C:3]([CH3:7])[CH:2]=1.[C:9](Cl)(=[O:12])[CH:10]=[CH2:11].[Cl-].[Al+3].[Cl-].[Cl-]>ClCCl>[CH3:8][C:1]1[CH:2]=[C:3]([CH3:7])[CH:4]=[CH:5][C:6]=1[C:9](=[O:12])[CH:10]=[CH2:11]

Participants

5

Reactant 3

HCID 7929M-XyleneHCID 13140Acryloyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 46913387HCID 46913387, compoundYield 16%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Metaxylene (128 mg), acryloyl chloride (154 mg), and aluminium chloride (160 mg) were reacted in dichloromethane (1.5 mL) at from 0° C. to room temperature for 4 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (31 mg).

Workup

  1. additionThe resultant was treated in the same manner

Sources & evidence

ORD record
ord-01f77adf0f444d15aa26c24b30357cdb
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

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