Chlorobenzene → 1-(4-Chlorophenyl)-2-propen-1-one

HRID 1428459Notes

Reaction equation

HRID 1428459 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:8](Cl)(=[O:11])[CH:9]=[CH2:10].[Cl-].[Al+3].[Cl-].[Cl-]>ClCCl>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:11])[CH:9]=[CH2:10])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 7964ChlorobenzeneHCID 13140Acryloyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 109208881-(4-Chlorophenyl)-2-propen-1-one

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Chlorobenzene (0.3 mL), acryloyl chloride (120 mg), and aluminium chloride (115 mg) were reacted in dichloromethane (1 mL) at from 0° C. to room temperature for 4 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (390 mg).

Workup

  1. additionThe resultant was treated in the same manner

Sources & evidence

ORD record
ord-5088fda261aa492392b1e63b3f95153f
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

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