Pyridine → HCID 17853188, compound

HRID 1428460Notes

Reaction equation

HRID 1428460 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:7](Cl)(=[O:10])[CH:8]=[CH2:9].[Cl-].[Al+3].[Cl-].[Cl-]>ClCCl>[C:7]([C:4]1[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=1)(=[O:10])[CH:8]=[CH2:9]

Participants

5

Reactant 3

HCID 1049PyridineHCID 13140Acryloyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 17853188HCID 17853188, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Pyridine (0.5 mL), acryloyl chloride (120 mg), and aluminium chloride (150 mg) were reacted in dichloromethane (1 mL) at from 0° C. to room temperature for 2 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (37.9 mg).

Workup

  1. additionThe resultant was treated in the same manner

Sources & evidence

ORD record
ord-89e92d9130834254b86b28838a285e5d
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

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