Formaldehyde → HCID 86673230, compound

HRID 1428461Notes

Reaction equation

[C:1]([C:4]1[CH:8]=[CH:7][S:6][CH:5]=1)(=[O:3])[CH3:2].[CH:9]([NH:12][CH2:13]CO)([CH3:11])[CH3:10].C=O.[O:18]1CCO[CH2:20][CH2:19]1>>[OH:18][CH2:19][CH2:20][C:9]([NH:12][CH2:13][CH2:2][C:1]([C:4]1[CH:8]=[CH:7][S:6][CH:5]=1)=[O:3])([CH3:10])[CH3:11]

Participants

Reactant 4

HCID 712Formaldehyde

HCID 79942-(Isopropylamino)ethanol

HCID 151161-(Thiophen-3-yl)ethanone

HCID 312751,4-Dioxane

Product 1

HCID 86673230HCID 86673230, compound

Procedure

3-acetylthiophene (121 mg), isopropyl-2-hydroxyethyl amine (126 mg), and paraformaldehyde (36 mg) were reacted in dioxane (0.2 ml) at 130° C. for 2 hours.

Sources & evidence

ORD record: ord-14669ab0748643bb8883911a101244ea
Source dataset: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08937091B2

Reaction notes

Loading…