3-Butyn-1-OL → HCID 86690328, compound

HRID 1428678Notes

Reaction equation

HRID 1428678 reaction equation
[NH2:1][C:2]1[C:3](C#CCCCCC(O)=O)=[N:4][C:5]([C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)[N:7]=1.[CH2:31]([OH:35])[CH2:32][C:33]#[CH:34]>>[NH2:1][C:2]1[C:3]([C:34]#[C:33][CH2:32][CH2:31][OH:35])=[N:4][C:5]([C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)[N:7]=1

Participants

3

Reactant 2

HCID 135663-Butyn-1-OLHCID 86690320HCID 86690320, compound

Product 1

HCID 86690328HCID 86690328, compound

Procedure

The title compound was prepared analogously to 7-(3-amino-5,6-di-p-tolylpyrazin-2-yl)hept-6-ynoic acid (Ex 7 step 1) by replacing hept-6-ynoic acid with but-3-yn-1-ol;

Sources & evidence

ORD record
ord-0ec872c8421a4a2ca5340961801a7ce9
Source dataset
uspto-grants-2015_01
Patent number
US08937069B2

Reaction notes

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