HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,6,7,8-Tetrahydro-2-naphthylamine → 1-(4-oxo-3,4,6,7,8,9-hexahydro-benzo[g]quinazolin-2-yl)-1H-pyrazole-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,6,7,8-Tetrahydro-2-naphthylamine | HCID 75193 | — |
| Reactant | 1-(1-oxo-1,2,7,8,9,10-hexahydro-benzo[f]quinazolin-3-yl)-1H-pyrazole-4-carboxylic acid ethyl ester | HCID 136337182 | — |
| Product | 1-(4-oxo-3,4,6,7,8,9-hexahydro-benzo[g]quinazolin-2-yl)-1H-pyrazole-4-carboxylic acid ethyl ester | HCID 136337181 | — |
Reaction Steps
The titled compound was prepared in a manner analogous to Example 131, steps A-B, using 5,6,7,8-tetrahydro-naphthalen-2-ylamine in step A. Step B yielded a 2:1 mixture of the titled compound and 1-(1-oxo-1,2,7,8,9,10-hexahydro-benzo[f]quinazolin-3-yl)-1H-pyrazole-4-carboxylic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08937078B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-185c4996f7294a8cb135dc87f8f4665f |
| Source note | uspto-grants-2015_01 |