HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Bromo-1-(4-fluoro-3-methylphenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-(4-Fluoro-3-methylphenyl)ethan-1-one | HCID 289328 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Bromo-1-(4-fluoro-3-methylphenyl)ethanone | HCID 10977301 | — |
Reaction Steps
5.1 mL bromine was added to 15 g 4-fluor-3-methylacetophenone in 80 mL concentrated acetic acid. The reaction was stirred 3 h at RT. The reaction was added to water. The precipitate was filtered and dried to give 20.6 g desired product. Rt: 1.37 min (method I), (M+H)+: 231
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08937176B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-6e9b797b55e141d3830feb44f6dcd136 |
| Source note | uspto-grants-2015_01 |