HCID 5135059, compound → HCID 69258588, compound

Participants

Reaction Steps

Part A: Ethyl 2-methyl-1-phenyl-1H-imidazole-4-carboxylate (4.8 gram, 21% yield) was prepared according to the procedure described (in J. Heterocyclic Chem. 1987, 24, 1757-1763) from ethyl 3-anilino-2-nitro-acrylate (23.6 gram, 0.01 mol) and triethylorthoacetate (150 ml). The initially formed crude product was purified by flash chromatography (eluent: diethyl ether). Rf (diethylether˜0.15) to give pure ethyl 2-methyl-1-phenyl-1H-imidazole-4-carboxylate as an oil.

Provenance & Evidence