化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Azide → Cis-3-azido-6-benzhydryl-tetrahydropyran
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Azide | HCID 33557 | — |
| 反応物 | Methanesulfonic acid trans-6-benzhydryl-tetra-hydropyran-3-yl ester | HCID 11566406 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Cis-3-azido-6-benzhydryl-tetrahydropyran | HCID 11630718 | 92% |
反応手順
Trans-2-diphenylmethyl-tetrahydropyran-5-yl methanesulfonate 13 (0.39 g, 1.12 mmol) in dry DMF (50 ml) was reacted with sodium azide (0.22 g, 3.35 mmol) to yield cis-5-azido-2-diphenylmethyl-tetrahydropyran 14 (0.3 g, 92%) as an oil (Procedure B).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08937189B2 |
| 出典データセット | uspto-grants-2015_01 |
| ORD ID | ord-bee33b809649455592e87c681e3aa0d8 |
| 出典メモ | uspto-grants-2015_01 |