HCID 68008906, compound → HCID 68008617, compound

HRID 1429076Notes

Reaction equation

C(OC(N[C@@H]1C(=O)N2C[C@H](OC3C=NC4C(=CC=CC=4)N=3)C[C@H]2C(=O)N[C@]2(C(OCC)=O)C[C@H]2CC(F)(F)CCCCC1)=O)(C)(C)C.[C:48]([O:52][C:53]([NH:55][C@@H:56]1[C:70](=[O:71])[N:69]2[CH2:72][C@H:73]([O:75][C:76]3[C:85]([CH3:86])=[N:84][C:83]4[C:78](=[CH:79][CH:80]=[CH:81][CH:82]=4)[N:77]=3)[CH2:74][C@H:68]2[C:67](=[O:87])[NH:66][C@:65]2([C:89]([O:91]CC)=[O:90])[CH2:88][C@H:64]2[CH2:63][C:62]([F:95])([F:94])[CH2:61][CH2:60][CH2:59][CH2:58][CH2:57]1)=[O:54])([CH3:51])([CH3:50])[CH3:49]>>[C:48]([O:52][C:53]([NH:55][C@@H:56]1[C:70](=[O:71])[N:69]2[CH2:72][C@H:73]([O:75][C:76]3[C:85]([CH3:86])=[N:84][C:83]4[C:78](=[CH:79][CH:80]=[CH:81][CH:82]=4)[N:77]=3)[CH2:74][C@H:68]2[C:67](=[O:87])[NH:66][C@:65]2([C:89]([OH:91])=[O:90])[CH2:88][C@H:64]2[CH2:63][C:62]([F:94])([F:95])[CH2:61][CH2:60][CH2:59][CH2:58][CH2:57]1)=[O:54])([CH3:51])([CH3:49])[CH3:50]

Participants

Reactant 2

HCID 68008906HCID 68008906, compound

HCID 68009101HCID 68009101, compound

Product 1

HCID 68008617HCID 68008617, compound

Procedure

Example 3b was prepared according to the procedure utilized for the preparation of Example 1 g, replacing the product of Example 1f with the product of Example 3a.

Workup

customExample 3b was prepared

Sources & evidence

ORD record: ord-afee276b275d4601b2406d491920226e
Source dataset: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08937041B2

Reaction notes

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