O-Phenylenediamine → HCID 178517134, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of ethyl 2-(benzofuran-2-yl)-2-oxoacetate (Example 15a, 237 mg, 1.09 mmol) in EtOH (2.7 mL) was added o-phenylenediamine (117 mg, 1.09 mmol). The reaction mixture was stirred at 90° C. for 16 h (a yellow solid appeared quickly). The mixture was cooled to 0° C., filtered, and the solid rinsed with cold EtOH. The yellow solid was azeotroped with CHCl3 and benzene and dried to provide the title compound (268 mg, 94% yield).

Provenance & Evidence