HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68592522, compound → HCID 68589639, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68592522 | HCID 68592522 | — |
| Catalyst | (1,3-Bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene)(dichloro)((2-((propan-2-yl)oxy)phenyl)methylidene)ruthenium | HCID 11763533 | — |
| Product | HCID 68589639 | HCID 68589639 | 38.1% |
Reaction Steps
Compound 7c (1 g, 1.69 mmol) and Hoveyda-Grubbs catalyst, 2nd generation (100 mg) were dissolved in degassed and dry DCE (1000 ml). The mixture was heated to reflux temperature over night under N2-atmosphere. The material was mixed with silica and the solvent was evaporated. Purification by column chromatography, EtOAc/Heptane 30:70→50:50 gave the title compound (362 mg, 38%), MS (M+H)+563.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08937080B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-e43c10bf93b743a5bd85fe6f306b167e |
| Source note | uspto-grants-2015_01 |