HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68590970, compound → HCID 68590866, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68590970 | HCID 68590970 | — |
| Catalyst | (1,3-Bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene)(dichloro)((2-((propan-2-yl)oxy)phenyl)methylidene)ruthenium | HCID 11763533 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 68590866 | HCID 68590866 | 72.2% |
Reaction Steps
To a solution of the diolefin 13c (760 mg, 1.28 mmol) in DCE (700 ml) under argon (three times evaporated three times filled with argon) was added Hoveyda Grubbs catalyst 2nd generation (80 mg) and the mixture was refluxed overnight. The solvent was evaporated under reduced pressure and the residue was purified by silica gel chromatography with hexane ethyl acetate which gave the title compound (0.52 g, 70%), (M+H)+563.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08937080B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-954fa6f7c71142299a85d9362fd85764 |
| Source note | uspto-grants-2015_01 |