HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 68590505, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 68590308 | HCID 68590308 | — |
| Reactant | HCID 86641378 | HCID 86641378 | — |
| Product | HCID 68590505 | HCID 68590505 | 82% |
Reaction Steps
The acid 16c (1.2 g, 2 mmol) was reacted with N-methylhexeneamine (340 mg, 3.0 mmol) and DIEA (1.29 g, 10.0 mmol) in dry DMF (30 ml) according to the procedure described in Example 13 step c. Purification by column chromatography on silica gel gave the title compound, (1.02 g, 82%), (M+H)+621.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08937080B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-09ff335a3afd41f095305fb521cbc2bf |
| Source note | uspto-grants-2015_01 |