HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 68592856, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 68590782 | HCID 68590782 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | HCID 68592856 | HCID 68592856 | 77% |
Reaction Steps
A solution of the ethyl ester 16e (1.2 g, 2 mmol) in THF/MeOH 1:1 (30 ml) was treated with a 1M solution of LiOH as described in Example 13 step d. Purification by column chromatography on silica gel gave the crude title compound, (400 mg, 77%), (M+H)+565.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08937080B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-fa22655053c2431eb22a5d43eb42462f |
| Source note | uspto-grants-2015_01 |