HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromophenylalanine → Methyl 2-amino-3-(4-bromophenyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromophenylalanine | HCID 85681 | — |
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Product | Methyl 2-amino-3-(4-bromophenyl)propanoate | HCID 21921420 | 92% |
Reaction Steps
A mixture of 2-amino-3-(4-bromophenyl)propanoic acid 3c (24.4 g, 100 mmol) in HCl/MeOH (300 mL) was stirred at reflux overnight. TLC analysis indicated the total consumption of compound 3c. The mixture was concentrated to give 3d as a pale yellow solid (24 g, 92% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940722B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-966329986bdc4a8d80e563a78e7347fe |
| Source note | uspto-grants-2015_01 |