HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylbenzoic acid → Methyl o-toluate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylbenzoic acid | HCID 8373 | — |
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Product | Methyl o-toluate | HCID 33094 | 82% |
Reaction Steps
A solution of 2-methylbenzoic acid (18a) (5 g, 36.8 mmol) in MeOH.HCl (2.4M, 50 mL) was stirred at 70° C. overnight. The mixture was concentrated under reduced pressure to give compound 18b (4.5 g, 82% yield), which was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940722B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-8e08b5ce0bd64da0b3e178046c5c3c67 |
| Source note | uspto-grants-2015_01 |