(R)-tert-Butyl(1-((2-(bromomethyl)benzyl)oxy)pent-4-en-2-yl)carbamate → (R)-1((2-(Bromomethyl)benzyl)oxy)pent-4-en-2-amine

Participants

Reaction Steps

A solution of compound 18j (2.8 g, 7.3 mmol) in TFA/DCM (25 mL, v/v=1/4) was stirred at rt for 1 hr. The mixture was concentrated under reduced pressure to give compound 18k (2.0 g, 98% yield), which was used without purification. LCMS (m/z): 285.1 (MH+).

Provenance & Evidence