Pyridine → HCID 71269471, compound

Participants

Reaction Steps

A solution of compound 23 (100 mg, 0.24 mmol), pyridine (47 mg, 0.6 mmol) and (CF3CO)2O (76 mg, 0.36 mmol) in DCM (5 mL) was stirred at it for 2 hr. The reaction mixture was quenched with water and extracted with DCM. The organic extracts were dried over anhydrous Na2SO4, filtered and concentrated. The crude product was purified by Prep-TLC to give the desired compound 24 (34 mg, 36% yield). LCMS (m/z): 394.2 (MH+).

Provenance & Evidence