Ethyl Acetate → HCID 68233570, compound

Participants

Reaction Steps

30h (1.8 g, 4.55 mmol) in THF (5 mL) was added dropwise to a stirred solution of LiAlH4 (0.35 g, 9.1 mmol) in THF (25 mL) at 0° C. Then the mixture was stirred at rt until TLC analysis indicated the total consumption of the SM. The reaction was quenched carefully by the slow addition of water (10 mL), and then the liquid was decanted away from the precipitate. The precipitate was washed with DCM (3×50 mL) and the organic layers were combined and dried over Na2SO4. The solvent was removed and the residue was purified by CC using PE:EA=5:1 as mobile phase to afford the desired product (1.3 g, 79% yield).

Provenance & Evidence