HCID 68233453, compound → (R,E)-4-Amino-5-phenylpent-2-enenitrile

HRID 1429407Notes

Reaction equation

HRID 1429407 reaction equation
C(OC(=O)[NH:7][C@@H:8](/[CH:16]=[CH:17]/[C:18]#[N:19])[CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)(C)(C)C>Cl.CO>[NH2:7][C@H:8]([CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)/[CH:16]=[CH:17]/[C:18]#[N:19]

Participants

3

Reactant 1

HCID 68233453HCID 68233453, compound

Product 1

HCID 68233458(R,E)-4-Amino-5-phenylpent-2-enenitrile

Reagents, catalysts & solvents 1

HCID 21893726Hydrochloride methanolSolvent

Procedure

Compound 31e (4.0 g, 14.7 mmol) was treated with 2M HCl/MeOH (300 mL). After the reaction was over, the solvents were removed under reduced pressure to give a white solid. The product was directly used in the next reaction step without further purification.

Workup

  1. customwere removed under reduced pressure
  2. customto give a white solid
  3. customThe product was directly used in the next reaction step without further purification

Sources & evidence

ORD record
ord-19eb24d404ee4e0ababa86f73d24d572
Source dataset
uspto-grants-2015_01
Patent number
US08940722B2

Reaction notes

Loading…