HRID1429640

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID55262854

未命名化合物

结构：CC(C)(C)OC(=O)NC1=N[C@@]2(c3cc(N)ccc3F)CO[C@H](C(F)(F)F)[C@H]2CS1

HCID68171522

未命名化合物

PRODUCTS

生成物

结构：NC1=N[C@@]2(c3cc(NC(=O)c4cnc(C(F)(F)F)cn4)ccc3F)CO[C@H](C(F)(F)F)[C@H]2CS1

HCID57523782

未命名化合物

PROCEDURE

实验过程

Synthesized from tert-butyl[(4aS,5S,7aS)-7a-(5-amino-2-fluorophenyl)-5-trifluoromethyl-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-yl]carbamate and 5-trifluoromethylpyrazine-2-carboxylic acid according to the general procedure. 1H NMR (400 MHz, CDCl3) δ ppm 2.80 (dd, J=13 0.6, 3.8 Hz, 1 H), 3.11 (dd, J=13.8, 2.9 Hz, 1 H), 3.30-3.44 (m, 1 H), 3.87 (d, J=8.3 Hz, 1 H), 4.25-5.14 (m, 4 H), 7.07 (dd, J=11.9, 8.8 Hz, 1 H), 7.57 (dd, J=6.8, 2.8 Hz, 1 H), 7.86 (dt, J=8.4, 3.6 Hz, 1 H), 8.89 (s, 1 H), 9.53 (s, 2 H)