HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 57417082, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 58092718 | HCID 58092718 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 57417082 | HCID 57417082 | — |
Reaction Steps
A solution of (2S,4S)-4-Dimethylamino-pyrrolidine-2-carboxylic acid butyl ester (326 mg) and 7M ammonia in methanol (8 ml) is stood for 18 hours at room temperature in a sealed vessel. Filtration, evaporation and trituration with diethyl ether/methanol gives the title compound as a beige solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940771B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-de874e35c89745718d9dad7254754fea |
| Source note | uspto-grants-2015_01 |