Ammonia → HCID 57420320, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of (3R,7aR)-7a-dimethylaminomethyl-3-trichloromethyl-tetrahydro-pyrrolo[1,2-c]oxazol-1-one (0.26 g) and 7M ammonia in methanol (4 ml) is heated at 50° C. for 3 days in a sealed vessel. The cooled reaction mixture is then evaporated to give the title compound as a brown oil which is used without further purification.

Provenance & Evidence