HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 57417080, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Methyl (4R)-4-(dimethylamino)-L-prolinate | HCID 51072228 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 57417080 | HCID 57417080 | — |
Reaction Steps
A solution of (2S,4R)-4-Dimethylamino-pyrrolidine-2-carboxylic acid methyl ester (225 mg) and 7M ammonia in methanol (7 ml) is stood for 18 hours at room temperature in a sealed vessel. Evaporation and trituration with diethyl ether gives the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940771B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-996118a1c14f4f54909fb351e4d91fee |
| Source note | uspto-grants-2015_01 |