Sodium ion → 4-Methyl-2-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-8-(1-propan-2-ylpiperidin-4-yl)oxy-3,4-dihydropyrazino[1,2-a]indol-1-one

HRID 143016Notes

Reaction equation

HRID 143016 reaction equation
[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([O:10][c:11]2[cH:12][c:13]3[cH:14][c:15]4[n:16]([c:17]3[cH:18][cH:19]2)[CH:20]([CH3:25])[CH2:21][NH:22][C:23]4=[O:24])[CH2:8][CH2:9]1.[Cl:28][CH2:29][c:30]1[n:31][o:32][c:33](-[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[n:34]1.[H-:26].[Na+:27]>>[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([O:10][c:11]2[cH:12][c:13]3[cH:14][c:15]4[n:16]([c:17]3[cH:18][cH:19]2)[CH:20]([CH3:25])[CH2:21][N:22]([CH2:29][c:30]2[n:31][o:32][c:33](-[c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[n:34]2)[C:23]4=[O:24])[CH2:8][CH2:9]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 166653HydrideHCID 3021543-(Chloromethyl)-5-phenyl-1,2,4-oxadiazoleHCID 684633554-methyl-8-(1-propan-2-ylpiperidin-4-yl)oxy-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one

Product 1

HCID 684649394-Methyl-2-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-8-(1-propan-2-ylpiperidin-4-yl)oxy-3,4-dihydropyrazino[1,2-a]indol-1-one

Sources & evidence

ORD record
ord-4e14010f7dcb43158aa91718203692ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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