m-(Dimethylamino)benzyl alcohol → HCID 86681307, compound

HRID 1430252Notes

Reaction equation

HRID 1430252 reaction equation
CN(C)[C:3]1[CH:4]=[C:5]([CH2:9][OH:10])[CH:6]=[CH:7][CH:8]=1.[Br:12][C:13]1[C:14]([CH3:20])=[C:15](O)[CH:16]=[CH:17][CH:18]=1.CC1(C)C(C)(C)OB(C2C=NNC=2)O1>>[Br:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:10][CH2:9][CH:5]2[CH2:6][CH2:7][CH2:8][CH2:3][CH2:4]2)[C:14]=1[CH3:20]

Participants

4

Reactant 3

HCID 90133m-(Dimethylamino)benzyl alcoholHCID 27740104-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 111714303-Bromo-2-methylphenol

Product 1

HCID 86681307HCID 86681307, compound

Procedure

The title compound was prepared by substituting cyclohexylmethanol for (3-(dimethylamino)phenyl)methanol and 3-bromo-2-methylphenol for 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 34A.

Sources & evidence

ORD record
ord-7cfe1d72d2aa443a85c713aae1fcc65a
Source dataset
uspto-grants-2015_01
Patent number
US08940737B2

Reaction notes

Loading…