Acetic Acid → HCID 89498315, compound

Participants

Reaction Steps

A suspension of EXAMPLE 133A (20 mg), benzaldehyde (6.58 μL), MP-CNBH3 (100 mg, 2.47 mmol/g), acetic acid (2 μL) in dichloromethane (2 mL)/methanol (2 mL) was shaken at room temperature for 18 hours. The reaction mixture was filtered, washed with methanol/dichloromethane, concentrated and purified by RP HPLC(C8, 30-100% CH3CN/water/0.1% TFA) to provide the title compound.

Provenance & Evidence