4-Bromopyrazole → HCID 61028673, compound

HRID 1430287Notes

Reaction equation

HRID 1430287 reaction equation
C[N:2]([CH3:11])[C:3]1C=[C:5]([CH2:9][OH:10])[CH:6]=[CH:7][CH:8]=1.[Br:12][C:13]1C=N[NH:16][CH:17]=1.CC1(C)C(C)(C)OB(C2C=NNC=2)O1>>[Br:12][C:13]1[CH:17]=[N:16][N:2]([CH2:3][CH:8]2[CH2:7][CH2:6][CH2:5][CH2:9][O:10]2)[CH:11]=1

Participants

4

Reactant 3

HCID 163754-BromopyrazoleHCID 90133m-(Dimethylamino)benzyl alcoholHCID 27740104-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product 1

HCID 61028673HCID 61028673, compound

Procedure

The title compound was prepared by substituting (tetrahydro-2H-pyran-2-yl)methanol for (3-(dimethylamino)phenyl)methanol and 4-bromo-1H-pyrazole for 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 34A.

Sources & evidence

ORD record
ord-f9d8d01bc9784b4ebc0a30ee9e39d582
Source dataset
uspto-grants-2015_01
Patent number
US08940737B2

Reaction notes

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