反应详情

温度

40 °C

To a solution of lead tetraacetate (4.3 g, 9.7 mmol) in dry chloroform (15 ml) at 40° C. is added 3,5-dimethylbiphen-4-ylboronic acid (2.0 g, 8.8 mmol) in one portion under an atmosphere of nitrogen. The reaction mixture is stirred at 40° C. for 4 hours, and then is cooled to room temperature and filtered, washing the residual solid with chloroform (50 ml). The filtrate is filtered through a plug of potassium carbonate on diatomaceous earth and the filtrate is evaporated to afford 3,5-dimethylbiphen-4-yllead triacetate. The reagent is diluted in chloroform and used as a standard solution.

1. temperatureis cooled to room temperature
2. filtrationfiltered
3. washwashing the residual solid with chloroform (50 ml)
4. filtrationThe filtrate is filtered through a plug of potassium carbonate on diatomaceous earth
5. customthe filtrate is evaporated