HCID 23093062, compound → HCID 86659565, compound

HRID 1431024Notes

Reaction equation

HRID 1431024 reaction equation
C([O:3][P:4]([CH2:9][NH:10][C:11]([C:13]1[S:17][C:16]([NH2:18])=[N:15][C:14]=1[CH3:19])=[O:12])(=[O:8])[O:5]CC)C.[CH:20]([O:23][C:24]1[CH:25]=[C:26]([CH:30]=[C:31]([O:33][C:34]2[CH:39]=[CH:38][C:37]([S:40]([CH3:43])(=[O:42])=[O:41])=[CH:36][CH:35]=2)[CH:32]=1)[C:27](O)=[O:28])([CH3:22])[CH3:21]>>[CH:20]([O:23][C:24]1[CH:25]=[C:26]([CH:30]=[C:31]([O:33][C:34]2[CH:39]=[CH:38][C:37]([S:40]([CH3:43])(=[O:42])=[O:41])=[CH:36][CH:35]=2)[CH:32]=1)[C:27]([NH:18][C:16]1[S:17][C:13]([C:11]([NH:10][CH2:9][P:4](=[O:8])([OH:3])[OH:5])=[O:12])=[C:14]([CH3:19])[N:15]=1)=[O:28])([CH3:22])[CH3:21]

Participants

3

Reactant 2

HCID 23093062HCID 23093062, compoundHCID 86659566HCID 86659566, compound

Product 1

HCID 86659565HCID 86659565, compound

Procedure

The title compound is prepared from {[(2-amino-4-methyl-thiazole-5-carbonyl)-amino]-methyl}-phosphonic acid diethyl ester and 3-isopropoxy-5-(4-methanesulfonyl-phenoxy)-benzoic acid in a similar manner to Example 21.

Sources & evidence

ORD record
ord-71fcf54be19145e282a101bb272f5855
Source dataset
uspto-grants-2015_01
Patent number
US08940927B2

Reaction notes

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