Pyridine → HCID 67507950, compound

Participants

Reaction Steps

The ester was prepared according to Procedure A using diethyl 2-methylmalonate (6.00 mL, 34.9 mmol), pyridine (3.76 mL, 46.5 mmol) and 2-bromoaniline (4.00 g, 23.3 mmol). The residue was purified by column chromatography on silica gel (0-30% EtOAc/hexane) to give ethyl 3-(2-bromophenylamino)-2-methyl-3-oxopropanoate as a yellow solid. Mass Spectrum (ESI) m/e=300.0 (M+1).

Provenance & Evidence