HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Tributylstannyl)pyridine → 4,8-Dichloro-3-methyl-2-(pyridin-2-yl)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Tributylstannyl)pyridine | HCID 607784 | — |
| Reactant | 2,4,8-Trichloro-3-methylquinoline | HCID 59631217 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4,8-Dichloro-3-methyl-2-(pyridin-2-yl)quinoline | HCID 59631035 | — |
Reaction Steps
The dichloride was prepared according to Procedure E using 2,4,8-trichloro-3-methylquinoline (0.475 g, 1.927 mmol), 2-(tributylstannyl)pyridine (0.780 mL, 2.120 mmol), palladium tetrakistriphenylphosphine (0.223 g, 0.193 mmol) in toluene (3.85 mL) to give 4,8-dichloro-3-methyl-2-(pyridin-2-yl)quinoline as a white solid. Mass Spectrum (ESI) m/e=289.0 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940724B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-d6e6a1aa80de42d5a150a9a0d857fa29 |
| Source note | uspto-grants-2015_01 |