2-(Tributylstannyl)pyridine → HCID 59631307, compound

Participants

Reaction Steps

The Stille coupled product was prepared according to Procedure E using 2,4,8-trichloro-7-fluoro-3-methylquinoline (0.6 g, 2.27 mmol), 2-(tributylstannyl)pyridine (0.877 g, 2.38 mmol), palladium tetrakistriphenylphosphine (0.26 g, 0.23 mmol) in toluene (2 mL) to give 4,8-dichloro-7-fluoro-3-methyl-2-(pyridin-2-yl)quinoline as a white solid. Mass Spectrum (ESI) m/e=307.0 (M+1).

Provenance & Evidence