2-(Tributylstannyl)pyridine → HCID 59631137, compound

Participants

Reaction Steps

The Stille coupled product was prepared according to Procedure E using 2,4,8-trichloro-5-fluoro-3-methylquinoline (0.61 g, 2.306 mmol), 2-(tributylstannyl)-pyridine (0.89 g, 2.42 mmol), palladium tetrakistriphenylphosphine (0.27 g, 0.23 mmol) in toluene (2 mL) to give 4,8-dichloro-5-fluoro-3-methyl-2-(pyridin-2-yl)-quinoline as a white solid. Mass Spectrum (ESI) m/e=307.0 (M+1).

Provenance & Evidence