2-(Tributylstannyl)pyridine → HCID 59631295, compound

Participants

Reaction Steps

The Stille coupled product was prepared according to Procedure E using 2,4,8-trichloro-5,7-difluoro-3-methylquinoline (0.3 g, 1.06 mmol), 2-(tributylstannyl)-pyridine (0.410 g, 1.12 mmol), palladium tetrakistriphenylphosphine (0.123 g, 0.106 mmol) in toluene (2 mL) to give 4,8-dichloro-5,7-difluoro-3-methyl-2-(pyridin-2-yl)quinoline as a tan solid. Mass Spectrum (ESI) m/e=325.0 (M+1).

Provenance & Evidence