2,4-Dichloro-5,7-difluoro-3-methylquinoline → HCID 59631051, compound

Participants

Reaction Steps

The Stille coupled product was prepared according to Procedure E using 2,4-dichloro-5,7-difluoro-3-methylquinoline (0.3 g, 1.21 mmol), 4-phenyl-2-(tributylstannyl)pyridine (0.591 g, 1.33 mmol), palladium tetrakistriphenylphosphine (0.140 g, 0.12 mmol) in toluene (2 mL) to give 4-chloro-5,7-difluoro-3-methyl-2-(4-phenylpyridin-2-yl)quinoline as a yellow solid. Mass Spectrum (ESI) m/e=367.0 (M+1).

Provenance & Evidence