HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Methylsulfinyl)phenylboronic acid → 4-Chloro-5,7-difluoro-3-methyl-2-(2-(methylsulfinyl)phenyl)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Methylsulfinyl)phenylboronic acid | HCID 2773529 | — |
| Reactant | 2,4-Dichloro-5,7-difluoro-3-methylquinoline | HCID 59631040 | — |
| Product | 4-Chloro-5,7-difluoro-3-methyl-2-(2-(methylsulfinyl)phenyl)quinoline | HCID 59631500 | — |
Reaction Steps
Essentially prepared according to Procedure F using 2,4-dichloro-5,7-difluoro-3-methylquinoline (250 mg, 1.00 mmol) and 2-(methylsulfinyl)phenylboronic acid to give 4-chloro-5,7-difluoro-3-methyl-2-(2-(methylsulfinyl)phenyl)quinoline. Mass Spectrum (ESI) m/e=352.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940724B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-d58593f32e4a42fd81aa4185f13afa66 |
| Source note | uspto-grants-2015_01 |