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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 143168Generated: October 26, 2026

Dimethyl Sulfoxide → 8-[5-(3-Methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]-1,4-dioxaspiro[4.5]decane-8-carboxamide

https://huagongshe.com/reaction/143168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantHydrogen PeroxideHCID 784—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantCarbonate IonHCID 19660—
Reactant8-[5-(3-Methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]-1,4-dioxaspiro[4.5]decane-8-carbonitrileHCID 67261700—
Product8-[5-(3-Methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]-1,4-dioxaspiro[4.5]decane-8-carboxamideHCID 67257794—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-68589e3ad8444386975851b5448c9ab7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)