HCID 59631038, compound → HCID 59631218, compound

HRID 1431751Notes

Reaction equation

HRID 1431751 reaction equation
[CH3:1][NH:2][C:3](=[O:19])[C:4]1[CH:9]=[C:8]([N+:10]([O-])=O)[CH:7]=[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)[CH:5]=1>[Pd].CO>[NH2:10][C:8]1[CH:9]=[C:4]([CH:5]=[C:6]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[CH:7]=1)[C:3]([NH:2][CH3:1])=[O:19]

Participants

4

Reactant 1

HCID 59631038HCID 59631038, compound

Product 1

HCID 59631218HCID 59631218, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Prepared according to Procedure V using N-methyl-3-morpholino-5-nitrobenzamide (0.183 g, 0.690 mmol), 10% palladium on carbon (0.011 g, 0.103 mmol), and methanol (3 mL) to afford 3-amino-N-methyl-5-morpholinobenzamide as a beige amorphous solid. Mass Spectrum (ESI) m/e=236.2 (M+1).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-3157583aa1bb4d8095fb18d74857d69b
Source dataset
uspto-grants-2015_01
Patent number
US08940724B2

Reaction notes

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