HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S,3R)-3-(2-butenyl)-2-hydroxysuccinic dimethyl ester → (2S,3R)-3-(n-butyl)-2-hydroxysuccinic dimethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S,3R)-3-(2-butenyl)-2-hydroxysuccinic dimethyl ester | HCID 86585708 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (2S,3R)-3-(n-butyl)-2-hydroxysuccinic dimethyl ester | HCID 23520166 | — |
Reaction Steps
To (2S,3R)-3-(2-butenyl)-2-hydroxysuccinic dimethyl ester B-2 (2.5 g) in EtOAc (50 mL) is added 10% Pd/C (0.25 g) and the reaction stirred under a hydrogen atmosphere for 20 hours. The suspension is filtered through Celite, washed with EtOAc (3×) and then concentrated in vacuo to afford (2S,3R)-3-(n-butyl)-2-hydroxysuccinic dimethyl ester B-3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612059B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-e6677eb734b14ac8a3076bcfe4b8dc1b |
| Source note | uspto-grants-2009_11 |