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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1431945Generated: November 2, 2026

4-(Pyrrolidin-2-yl)pyridine → (S)-hydroxy-3 (R)-[2-pyridin-4-yl-pyrrolidine-1-carbonyl)-heptanoic acid

https://huagongshe.com/reaction/1431945

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Pyrrolidin-2-yl)pyridineHCID 2771664—
Reactant2-(2,2-Dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acidHCID 22256526—
Product(S)-hydroxy-3 (R)-[2-pyridin-4-yl-pyrrolidine-1-carbonyl)-heptanoic acidHCID 86587585—

Reaction Steps

The title compound is prepared from 2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid B-5 and commercially available 4-pyrrolidin-2-yl-pyridine A-5 according to General Procedure B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612059B2
Source datasetuspto-grants-2009_11
ORD IDord-d0d50ff850ca4131a0261cebd6a81476
Source noteuspto-grants-2009_11